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Norovirus GI/GII

Test Code: H65008

Clinical Utility

This assay is only available as part of a panel and cannot be ordered individually.

Norovirus affects people of all ages and accounts for approximately 40 percent of nonbacterial outbreaks of diarrhea in the U.S.1,2 While infection with nontyphoidal Salmonella was the leading cause of hospitalization due to contaminated food in the US, Norovirus was second.3 Noroviruses are positive strand non-enveloped RNA viruses belonging to the family Caliciviridae. Norovirus infection causes nausea, vomiting, watery non-bloody diarrhea, and abdominal pain. Occasionally a low grade fever also occurs. Norovirus disease is usually self-limiting and rarely causes severe illness. While infections can occur year-round, Norovirus outbreaks tend to peak in cold weather.4,5

References

1.  Navaneetham U, Giannella RA. Mechanisms of infectious diarrhea.  Nat Clin Pract Gastroenterol Hepatol. 2008 Nov:5(11):637-47.

2.  Glass RI, Parashar UD, Estes MK. Norovirus gastroenteritis. N Engl J Med. 2009 Oct 29:361(18):1776-85.361(18):1776-1785.

3.  Scallan E, Hoekstra RM, Angula FJ, et al. Foodborne illness acquired in the United States--major pathogens. Emerg Infect Dis. 2011 Jan:17(1):7-15.

4.  Dennehy PH. Viral gastroenteritis in children. Pediatr Infect Dis J. 2011 Jan:30(1):63-4.

5.  Glass RI, Parashar UD, Estes MK. Norovirus gastroenteritis. N Engl J Med. 2009 Oct 29:361(18):1776-85.

Disclaimer

Specimens are approved for testing in New York only when indicated in the Specimen Information field above.

The CPT codes provided are based on Viracor-IBT's interpretation of the American Medical Association's Current Procedural Terminology (CPT) codes and are provided for general informational purposes only. CPT coding is the sole responsibility of the billing party. Questions regarding coding should be addressed to your local Medicare carrier. Viracor-IBT assumes no responsibility for billing errors due to reliance on the CPT codes illustrated in this material.

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