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Panton-Valentine leukocidin gene

Test Code: 202100

Clinical Utility

This assay is only available as part of a panel and cannot be ordered individually.

The pathogenicity of Staphylococcus aureus depends on various bacterial surface components and extracellular proteins. However, the precise role of single virulence determinants in relation to infection is hard to establish. The frequent recovery of staphylococcal isolates that produce leukocidal toxins from patients with deep skin and soft tissue infections, particularly furunculosis, cutaneous abscesses, and severe necrotizing pneumonia, suggests that the Panton-Valentine leukocidin (PVL) is 1 such virulence factor that has a major role in pathogenicity.*

*Source: http://wwwnc.cdc.gov/eid/article/12/7/05-0865_article

 

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