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Soluble IL-2 Receptor (sIL-2R) Serum

Test Code: 30057

Cpt Code:

84238 (x1)

Clinical Utility

sIL-2Ra appears in serum, concomitant with its increased expression on cells and correlates with increased activation of T and B cells. Studies suggest a correlation of levels of sIL-2Ra in serum with the onset of rejection episodes in allograft recipients, with activity of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus (SLE) and with the course of some leukemias and lymphomas.


Sandwich ELISA technique. sIL-2Ra binds to the specific monoclonal antibody that is pre-coated on a microplate. Bound sIL-2Ra is detected by an enzyme-linked sIL-2Ra specific monoclonal antibody. Substrate solution is added and color develops in proportion to the amount of sIL-2Ra bound. This test has not been cleared or approved for diagnostic use by the U.S. Food and Drug Administration.

Assay Range

The result is reported in pg/mL. The reference range for a healthy population is 622 - 1,619 pg/mL. However it should be noted that these ranges are obtained from a limited population of apparently healthy adults and are not diagnostic thresholds.

Turnaround Time

Set up T, F. TAT 7 days from receipt of specimen.

Specimen Information


NY approved.1 mL. Blood should be allowed to clot prior to centrifugation. Specimens should be frozen (-70 C). Ship overnight courier on dry ice.

Not stable ambient or refrigerated.


Specimens are approved for testing in New York only when indicated in the Specimen Information field above.

The CPT codes provided are based on Viracor-IBT's interpretation of the American Medical Association's Current Procedural Terminology (CPT) codes and are provided for general informational purposes only. CPT coding is the sole responsibility of the billing party. Questions regarding coding should be addressed to your local Medicare carrier. Viracor-IBT assumes no responsibility for billing errors due to reliance on the CPT codes illustrated in this material.



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