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Soluble IL-2 Receptor (sIL-2R) Serum

Test Code: 30057
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Clinical Utility

sIL-2Ra appears in serum, concomitant with its increased expression on cells and correlates with increased activation of T and B cells. Studies suggest a correlation of levels of sIL-2Ra in serum with the onset of rejection episodes in allograft recipients, with activity of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus (SLE) and with the course of some leukemias and lymphomas.

Procedure

Sandwich ELISA technique. sIL-2Ra binds to the specific monoclonal antibody that is pre-coated on a microplate. Bound sIL-2Ra is detected by an enzyme-linked sIL-2Ra specific monoclonal antibody. Substrate solution is added and color develops in proportion to the amount of sIL-2Ra bound. This test has not been cleared or approved for diagnostic use by the U.S. Food and Drug Administration.

7 business days from receipt of specimen

Specimen Type Order Code CPT Code NY Approved Volume Assay Range Special Instructions
serum 30057 84238 Yes 1 mL (min. 100 uL) 622-1619 pg/mL
  • Collect 1 mL, blood should be allowed to clot prior to centrifugation.
  • Specimens should be frozen (-70 C).
  • Ship overnight on dry ice.
  • Stability, not stable ambient or refrigerated.

The result is reported in pg/mL. The reference range for a healthy population is 622 - 1,619 pg/mL. However it should be noted that these ranges are obtained from a limited population of apparently healthy adults and are not diagnostic thresholds.

Specimens are approved for testing in New York only when indicated in the Specimen Information field above.

The CPT codes provided are based on Viracor Eurofins' interpretation of the American Medical Association's Current Procedural Terminology (CPT) codes and are provided for general informational purposes only. CPT coding is the sole responsibility of the billing party. Questions regarding coding should be addressed to your local Medicare carrier. Viracor Eurofins assumes no responsibility for billing errors due to reliance on the CPT codes illustrated in this material.

References

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