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Tryptase

Test Code: 44
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Clinical Utility

Tryptase is a neutral protease of molecular weight 134,000 that is found almost exclusively in mast cells. It is used as a marker to monitor and analyze reactions involving mast cells.

Procedure

Enzyme Immunoassay (FEIA). It is manufactured by Phadia for the UniCAP instrument. The performance characteristics of this test have been determined by Viracor Eurofins. This test has been cleared or approved for diagnostic use by the U.S. Food and Drug Administration.

3 business days from receipt of specimen

Specimen Type Order Code CPT Code NY Approved Volume Assay Range Special Instructions
plasma 44 83520 Yes

1 mL (min. 500 uL)

The result is reported in ng/mL. The assay range is approximately 1.0 to 200. The reference range for a healthy population is less than 11.4.

  • Collect 1 mL
  • The specimen can be stored for 3 weeks at 4 to 25° C.
  • Ship via overnight courier at ambient temperature.
  • During summer months ship overnight on dry ice or cold pack.
  • Stability 25 days ambient, 25 days refrigerated, >25 days frozen.
serum 44 83520 Yes

1 mL (min. 500 uL)

The result is reported in ng/mL. The assay range is approximately 1.0 to 200. The reference range for a healthy population is less than 11.4.

  • Collect 1 mL
  • The specimen can be stored for 3 weeks at 4 to 25° C.
  • Ship via overnight courier at ambient temperature.
  • During summer months ship overnight on dry ice or cold pack.
  • Stability 25 days ambient, 25 days refrigerated, >25 days frozen.

Specimens are approved for testing in New York only when indicated in the Specimen Information field above.

The CPT codes provided are based on Viracor Eurofins' interpretation of the American Medical Association's Current Procedural Terminology (CPT) codes and are provided for general informational purposes only. CPT coding is the sole responsibility of the billing party. Questions regarding coding should be addressed to your local Medicare carrier. Viracor Eurofins assumes no responsibility for billing errors due to reliance on the CPT codes illustrated in this material.

References

Schwartz LB et al J Biol Chem 1981; 256:11939-11943.

Schwartz LB et al N Engl J Med 1987; 316:1622-1626.

Schwartz LB et al. J Clin Invest 1995; 96:2702-2710.

Schwartz LB et al J Aller Clin Immun 1994;14:190-204.

Schwartz, LB et al J Clin Invest 1989; 83:1551-1555.

Randall B, Butts J and Halsey JF. J Forensic Sci 1995; 40:208-211.

Carias K, Rouse C, Schwartz LB. J Allergy Clin Immunol (Abstract) 1995.

Proud D et al J Aller Clin Immunol 1992; 89:1098-1110.

Rasp G and Hochstrasser K. Allergy 1993;48:72-74.

Horn KD, Halsey JF and Zumwalt RE Am J Foreusic Med Path 2004; 25:37-43.

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