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Walnut California Black Tree (Jugulans californica) IgG4

Test Code: 162822
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Clinical Utility

Physicians sometimes use allergen-specific IgG4 to monitor patients undergoing immunotherapy. Increasing IgG4 responses following the administration of immunotherapy generally correlate with a positive treatment outcome.

Procedure

Enzyme immunoassay (FEIA). A standard curve is used to calculate the specific IgG concentrations. The calibrators are referenced to the International Reference Preparation for serum immunoglobulins. This test has not been cleared or approved for diagnostic use by the U.S. Food and Drug Administration.

2-3 business days from receipt of specimen

Specimen Type Order Code CPT Code NY Approved Volume Assay Range Special Instructions
Serum 162822 86001 No 0.5 mL (min. 150 uL) See Limit of Quantitation Guide
  • Collect 1-2 mL whole blood in red top tube.
  • Centrifuge and transfer 0.5 mL serum into a transfer tube.
  • Ship at ambient or frozen temperature Monday through Friday.
  • Specimens are stable for 1 week ambient, 4 weeks refrigerated; freeze for storage greater than 4 weeks.
  mcg/mL of IgG4
Lower Limit of Quantitation 0.15
Upper Limit of Quantitation 30.0

Reference ranges vary by allergen.

Specimens are approved for testing in New York only when indicated in the Specimen Information field above.

The CPT codes provided are based on Viracor Eurofins' interpretation of the American Medical Association's Current Procedural Terminology (CPT) codes and are provided for general informational purposes only. CPT coding is the sole responsibility of the billing party. Questions regarding coding should be addressed to your local Medicare carrier. Viracor Eurofins assumes no responsibility for billing errors due to reliance on the CPT codes illustrated in this material.

References

Hamilton RG. Assessment of human allergic disease. In: Rich RR, Fleisher TA, Shearer WT, Kotzin BL and Schroeder HW (eds). Clinical Immunology, Principles & Practice, 2nd Ed., Chapter 124, Mosby, New York.

Specimen Volume Requirements

Calculate specimen volume needed for total number of IgE/ImmunoCAP allergens ordered

Dead Volume: 300 µL
Each Allergen: 40 µL

Enter the number of tests and click the Calculate button.

For panels, please include total test count.

*This calculator is intended to help assess appropriate specimen volume for IgE/ImmunoCAP allergen tests. Viracor Eurofins is not responsible for miscalculations and encourages clients to refer to test specific specimen volume requirements listed within the test menu, or to contact client services at 800-305-5198 with any questions.

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