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A frequent complication after transplantation, Cytomegalovirus (CMV) infection may cause a series of direct and indirect effects that lead to increased incidence of graft rejection, opportunistic infections, and decreased allograft and patient survival.1,2
1. Early Detection of CMV Reactivation, Primary Infections
2. Monitor Response to Treatment
3. Confirm Antiviral Resistance
4. Establish Immunity
Understand how your patient's immune system is responding to CMV medication.
Baseline & Monitor Viral Load
Quantitative CMV PCR can be used for early detection of reactivation, primary infection and monitoring response to treatment.
Dual gene targets and multiple probes increases the assay’s ability to pick up polymorphisms, therefore reducing the chance for false negatives and detecting other strains that could otherwise be missed.
Confirm Antiviral Resistance
Patient outcomes depend on effective prophylaxis and treatment with antiviral therapies, including ganciclovir, valganciclovir, foscarnet, cidofovir and letermovir.
Laboratory testing should be used to confirm drug resistance, as treatment modification based solely on clinical suspicion may result in added toxicity and increased complexity in patient management.
Establish Immunity
The CMV T Cell Immunity Panel measures the strength of T cell responses to CMV-specific antigens and reports the activity of CD4 and CD8 T cell responses independently.
Evaluating immunocompromised patients’ CMV-specific T cell response will help healthcare providers decide when to take patients off of antiviral medication during critical stages in treatment.
NEW RESEARCH ARTICLE:
Clinical experience with a novel assay measuring cytomegalovirus (CMV)-specific CD4+ and CD8+ T-cell immunity by flow cytometry and intracellular cytokine staining to predict clinically significant CMV events
Send your CMV testing to a lab that's leading the industry in CMV testing research and development. Read how Viracor is taking CMV clinical diagnostic testing to the next level.
Test Name | Test Code | Turnaround Time & Test Details | ||
PCR / Viral Load |
CMV Real-time Quantitative PCR |
5500 |
|
|
CMV Saliva Real-time PCR |
5571 |
|
||
Resistance |
CMV Resistance: Letermovir, Ganciclovir, Foscarnet, Cidofovir |
30721 |
|
|
5600 |
||||
30722 |
||||
Immunity | CMV T Cell Immunity Panel | 30360 |
|
Learn how we can help your hospital or lab streamline your CMV sample collection, turnaround time and testing results.
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EMAIL US1 Kotton CN, Kumar D, Caliendo AM, et al. International consensus guidelines on the management of cytomegalovirus in solid organ transplantation. Transplantation. Apr 15 2010;89(7):779-95.
2 Boeckh M, Ljungman P. How we treat cytomegalovirus in hematopoietic cell transplant recipients. Blood. 2009;113(23):5711-9.
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