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Benefits of Molecular PCR Testing for Chronic Wounds with Dr. Steve Kleiboeker, Vice President of Research and Development at Viracor

Learn how molecular PCR testing can aid in the diagnosis of chronic skin and soft tissue infections and combat the limitations of culture to improve patient outcomes.

Molecular PCR Testing: A fast, sensitive and accurate assessment of the true microbial diversity of wounds

Detect multiple pathogens simultaneously, improving the identification of key bacteria responsible for chronic, non-healing skin and soft tissue infections (SSTI).

Viracor Eurofins utilizes a target enriched multiplex polymerase chain reaction technology to deliver a cutting-edge panel for bacterial infection identification for wounds:

  • Identify and rule out bacterial pathogens; delivering actionable information to better manage antibiotic treatment
  • Detect bacteria in patients undergoing antibiotic treatment
  • Identify pathogens that are difficult or slow to culture
  • Same day results (within 8-12 hours from receipt of specimen) 
Detect multiple pathogens simultaneously, improving the identification of key bacteria responsible for chronic, non-healing skin and soft tissue infections (SSTI)

Molecular Testing Overcomes Three Key Limitations of Culture

Time, Bias and Interference of Antibiotics

Despite optimal specimen collection, culture bias and false negative results can be a real problem. Commensals may overgrow cultures and obscure the presence of pathogens. Some bacterial species will flourish under culture conditions, while others won't be detected. Biofilms, an ongoing issue for chronic wounds, are inherently polymicrobial. Culture can't identify these pathogens effectively.

In addition, culture cannot identify bacterial pathogens if the patient is undergoing antibiotic treatment.

CULTURE ISN'T WRONG, IT'S SIMPLY INCOMPLETE.

If you don't have the whole picture, how do you treat the whole wound?

With culture limiting our understanding of the true microbial composition of wound infections, what pathogens could you be missing? More critically, what pathogens are you not treating?

Timing is critical when treating chronic wounds, both for the patient's well being and the costs they will incur. Molecular testing will help you identify which pathogens are present and deliver actionable information to help you decide the appropriate course of treatment. 

Skin and Soft Tissue Infection Panel TEM-PCR™

TEST CODE 220798
Results reported same day (within 8 to 12 hours of receiving specimen)
Acinetobacter baumannii
Bacteroides spp.
Citrobacter freundii
Clostridium novyi / septicum
Clostridium perfringens
Enterobacter aerogenes
Enterobacter cloacae
Enterococcus faecalis
Enterococcus faecium
Escherichia coli
Kingella kingae
Klebsiella spp.
Morganella morganii
Proteus mirabilis
Proteus vulgaris
Pseudomonas aeruginosa
Staphylococcus aureus
  -MRSA
  -PVL gene
Staphylococcus lugdunensis
Streptococcus pyogenes (Group A)

Necrosis Panel TEM-PCR™

TEST CODE 220898
Results reported same day (within 8 to 12 hours of receiving specimen)
Bacteroides spp.
Clostridium novyi / septicum
Clostridium perfringens
Kingella kingae
Staphylococcus aureus
  -MRSA
  -PVL gene
Staphylococcus lugdunensis
Streptococcus pyogenes (Group A)

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