Diphtheria Antibody IgG
A common method for evaluating suspected antibody deficiency is to immunize the patient with an appropriately selected vaccine, such as Diphtheria, and determine vaccine-specific antibody concentrations in a serum sample 3-4 weeks post-immunization compared to a pre-immunization sample. A normal post-immunization response to these toxins is a 10 to 100-fold increase in antibody concentration compared to the pre-immunization sera. The recommended protective level of Diphtheria antitoxin IgG is greater than or equal to 0.10 IU/mL.
The toxin isolated from Corynebacterium diphtheriae is used as a solid phase antigen in a sensitive microtiter EIA. The EIA is calibrated by reference to the WHO International Reference Diphtheria anti-toxin lot NIBSC 00/496. This test has not been cleared or approved for diagnostic use by the U.S. Food and Drug Administration.
2-3 business days from receipt of specimen
|Specimen Type||Order Code||CPT Code||NY Approved||Volume||Assay Range||Special Instructions|
1 mL (min. 200 uL)
Specimens are approved for testing in New York only when indicated in the Specimen Information field above.
The CPT codes provided are based on Viracor Eurofins' interpretation of the American Medical Association's Current Procedural Terminology (CPT) codes and are provided for general informational purposes only. CPT coding is the sole responsibility of the billing party. Questions regarding coding should be addressed to your local Medicare carrier. Viracor Eurofins assumes no responsibility for billing errors due to reliance on the CPT codes illustrated in this material.
Smith TF J Resp Dis 1989;10: 12-29
Shapiro G. et al. Pediatrics 1991; 87: 311-316
Halsey, J. F. et al. J Allergy and Clin Immunol (abstr),1992;89:272
Siber G, et al Ped Infect. Dis. Journal 1989;8:S84-S91
Popa V, Kim K, Heiner D. Annals of Allergy 1993; 70:418 - 424.
Kilpatrick DC. Transfusion Medicine 2002; 121: 335-351.
Akira S et al. Nature Immunol 2002; 2: 675-680.